Clinical insights into a tertiary care center cohort of patients with bicuspid aortic valve

The team “Genetics and Development of Cardiac Defects” publishes in collaboration with the Department of Cardiology of “La Timone” Hospital the first study on a French cohort of patients with bicuspid aortic valve (BAV). Our project is designed to collect clinical and genetic data on consecutive patients prospectively admitted with a definite diagnosis of BAV. This study describes the clinical and echocardiographic spectrum of 223 consecutive BAV patients as they present in a tertiary care center and to determine factors associated with each type of valve degeneration. In this study we confirm high prevalence of valve dysfunction at first diagnosis of BAV in a referred population. The degenerative process differs according to type of dysfunction and is mainly dependent on age and gender.

Int J Cardiovasc Imaging. 2021 Aug 10. doi: 10.1007/s10554-021-02366-1