The H2020 Twinning projects aim to allow twinning between an institution from an associated country and at least two recognised laboratories of excellence located in EU member states. In this context, the SEED project was selected among 460 projects submitted. It started on 1 October 2019 for a period of 3 years. It brings together the University of Sfax (Tunisia), the Human Neurogenetics team of the MMG laboratory (AMU / Inserm U1251) and the University of Antwerp in Belgium. The project aims to develop new genetic analysis technologies (high throughput DNA sequencing) for the diagnosis of epileptic encephalopathies. These epilepsy phenotypes are associated with severe cognitive deficits for which there is an important genetic basis. The Human Neurogenetics team of MMG and the Belgian laboratory are experts in this field. During its 3 years of operation, the SEED program will also organize staff exchanges and e-learning activities, create a network of experts based in Tunisia for the Middle East and North Africa area and raise awareness among patient families through targeted dissemination and communication activities.