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Results: 1708  publications found.

Frankel, D.  et al. 2018

Detection of EGFR, KRAS and BRAF mutations in metastatic cells from cerebrospinal fluid

BACKGROUND: In lung adenocarcinoma, molecular profiling of actionable genes has become essential to set up targeted therapies. However, the feasibility and the relevance of molecular profiling from...
Clin. Chem. Lab. Med. - issue: 5 - volume: 56 - pages: 748-753.

Kitade, Y.  et al. 2018

Production of 4-Hydroxybenzoic Acid by an Aerobic Growth-Arrested Bioprocess Using Metabolically Engineered Corynebacterium glutamicum

Corynebacterium glutamicum was metabolically engineered to produce 4-hydroxybenzoic acid (4-HBA), a valuable aromatic compound used as a raw material for the production of liquid crystal polymers and...
Appl. Environ. Microbiol. - issue: 6 - volume: 84 - pages: .

Sanders, A.  et al. 2018

Using a Media Campaign to Increase Engagement With a Mobile-Based Youth Smoking Cessation Program

PURPOSE: To describe the impact of the National Cancer Institute's promotion of its youth smoking cessation program, Smokefree Teen (SFT). DESIGN: We provide a description of campaign strategies and...
Am J Health Promot - issue: 5 - volume: 32 - pages: 1273-1279.

Yauy, K.  et al. 2018

MoBiDiC Prioritization Algorithm, a Free, Accessible, and Efficient Pipeline for Single-Nucleotide Variant Annotation and Prioritization for Next-Generation Sequencing Routine Molecular Diagnosis

Interpretation of next-generation sequencing constitutes the main limitation of molecular diagnostics. In diagnosing myopathies and muscular dystrophies, another issue is efficiency in predicting the...
- issue: 4 - volume: 20 - pages: 465-473.

Eiler, S.  et al. 2018

Unstable Protein Purification Through the Formation of Stable Complexes

Purification of proteins containing disordered regions and participating in transient complexes is often challenging because of the small amounts available after purification, their heterogeneity,...
Methods Mol. Biol. - issue: - volume: 1764 - pages: 315-328.

Kheloufi, F.  et al. 2018

Chronic use of proton pump inhibitors, adverse events and potential biological mechanisms: A translational analysis

Proton pump inhibitors (PPIs) are among the most frequently prescribed drugs. Even if PPI are usually considered as safe, there is a growing concern for a range of adverse effects of chronic PPI...
- issue: - volume: - pages: .

Maurice, F.  et al. 2018

Active Cushing syndrome patients have increased ectopic fat deposition and bone marrow fat content compared to cured patients and healthy subjects: a pilot H-1-MRS study

Objective: Glucocorticoid excess is one of the most important causes of bone disorders. Bone marrow fat (BMF) has been identified as a new mediator of bone metabol ism. Cushing syndrome (CS) is a main...
- issue: 5 - volume: 179 - pages: 307-317.

Zaffran, S.  et al. 2018

Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations

Members of the large family of Hox transcription factors are encoded by genes whose tightly regulated expression in development and in space within different embryonic tissues confer positional...
- issue: - volume: - pages: .

Etchevers, H.  et al. 2018

Giant congenital melanocytic nevus with vascular malformation and epidermal cysts associated with a somatic activating mutation in BRAF

Giant congenital melanocytic nevi may be symptomatically isolated, or syndromic. Associations with capillary malformations are exceptional, and development of epidermal cysts has not been described. A...
- issue: - volume: - pages: .

Rajabally, YA.  et al. 2018


A systematic review of the literature was performed on the association of chronic inflammatory demyelinating polyneuropathy (CIDP) with malignancy. Hematological disorders are the most common...
- issue: 6 - volume: 57 - pages: 875-883.

Caulier, A.  et al. 2018

Primary red cell hydration disorders: Pathogenesis and diagnosis

Hydration status is critical for erythrocyte survival and is mainly determined by intracellular cation content. Active pumps, passive transporters, and ion channels are the key components of volume...
- issue: 1, SI - volume: 40 - pages: 68-73.

Sevy, A.  et al. 2018

Detection of proximal conduction blocks using a triple stimulation technique improves the early diagnosis of Guillain-Barre syndrome

Objective: Current diagnostic electrophysiological criteria can miss the early stages of Guillain-Barre syndrome (GBS). We evaluated the diagnostic efficiency of the triple stimulation technique (TST)...
- issue: 1 - volume: 129 - pages: 127-132.

Moore-Morris, T.  et al. 2018

Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages

Rationale: Myocardial infarction is a major cause of adult mortality worldwide. The origin(s) of cardiac fibroblasts that constitute the postinfarct scar remain controversial, in particular the...
- issue: 4 - volume: 122 - pages: 583-590.

Froudarakis, ME.  et al. 2018

Positive pleural cytology is an indicator for visceral pleural invasion in metastatic pleural effusions

IntroductionIn case of undiagnosed pleural effusions, it is necessary to conduct thoracentesis with pleural fluid (PF) cytology. Yet, sensitivity of PF cytology is widely variable as a result of...
- issue: 3 - volume: 12 - pages: 1011-1016.

Lescroart, F.  et al. 2018

Hox and Tale transcription factors in heart development and disease

Hox genes are highly conserved transcription factors with critical functions during development, in particular for patterning the antero-posterior axis of the embryo. Their action is very often...
- issue: 11-12 - volume: 62 - pages: 837-846.

Macagno, N.  et al. 2018

Reduced H3K27me3 Expression is Common in Nodular Melanomas of Childhood Associated With Congenital Melanocytic Nevi But Not in Proliferative Nodules Reply

- issue: 5 - volume: 42 - pages: 701-704.

Pitrez, PR.  et al. 2018

Substrate Topography Modulates Cell Aging on a Progeria Cell Model

Aging is characterized by a progressive accumulation of cellular damage, which leads to impaired function. Little is known whether substrates can influence cell aging. This is of utmost importance in...
- issue: 5 - volume: 4 - pages: 1498-1504.

Ludlow, AT.  et al. 2018

NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer

Alternative splicing is dysregulated in cancer and the reactivation of telomerase involves the splicing of TERT transcripts to produce full-length (FL) TERT. Knowledge about the splicing factors that...
- issue: - volume: 9 - pages: .

Bas, J.  et al. 2018

Motor unit number index correlates with disability in Charcot-Marie-Tooth disease

Objective: The aim of this study was to assess the usefulness of motor unit number index (MUNIX) tech-nique in Charcot-Marie-Tooth disease and test the correlation between MUNIX and clinical...
- issue: 7 - volume: 129 - pages: 1390-1396.

Vermalle, M.  et al. 2018

Lack of functional remission in Cushing's syndrome

Hypercortisolism leads to severe clinical consequences persisting after the onset of remission. These physical sequelae of cortisol exposure are known to profoundly impact the patient's quality of...
- issue: 3 - volume: 61 - pages: 518-525.